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Imagine a liposome as a tiny, bubble-like sphere, about the size of a virus or smaller. It's made up of fats called phospholipids, which naturally arrange themselves into a double layer—like two walls of soap bubbles stuck together. The outer and inner layers are "hydrophilic" (they love water), while the middle part sandwiched between them is "hydrophobic" (it hates water). This setup creates a waterproof compartment inside the bubble where water-soluble stuff (like nutrients or drugs) can be safely trapped and carried around, protected from the outside world. It's basically nature's version of a delivery capsule, mimicking how our own cell membranes are built!

Imagine a liposome as a tiny, bubble-like sphere, about the size of a virus or smaller. It's made up of fats called phospholipids, which naturally arrange themselves into a double layer—like two walls of soap bubbles stuck together. The outer and inner layers are "hydrophilic" (they love water), while the middle part sandwiched between them is "hydrophobic" (it hates water). This setup creates a waterproof compartment inside the bubble where water-soluble stuff (like nutrients or drugs) can be safely trapped and carried around, protected from the outside world. It's basically nature's version of a delivery capsule, mimicking how our own cell membranes are built!

Liposomes are defined as Phospholipid Vesicles consisting of one or

more Concentric Bilayers enclosing discrete aqueous spaces.

• Liposomes Improve biodistribution of compounds to target different sites in the

body;

• Liposomes enables effective delivery of encapsulated compounds to target sites

while minimizing systemic toxicity;

• Liposomes present as an attractive delivery system due to their Fexible

Physicochemical and Biophysical properties, which allow easy manipulation to

address different delivery considerations.

• Liposomes are the most common and well<investigated nano>carriers for targeted

active ingredient delivery.

• Liposomes overcome obstacles to cellular and tissue uptake, and improve

Biodistribution of compounds to target sites

• The unique ability of Liposomal systems to entrap both Lipophilic

and Hydrophilic compounds enable a diverse range of active

ingredients and nutrients to be encapsulated and delivered by

these vesicles.

• Encapsulation within Liposomes protects compounds from early

inactivation, degradation and dilution in the circulation of the

body.

• Liposomes are generally considered to be Pharmacologically

inactive with minimal toxicity, as they tend to be composed of

natural phospholipids.

How does a Fulvisomes / Fulvic Acid Liposomes deliver nutrients ?

Okay, let me break this down for you super simply, like we're just chatting over coffee. Imagine you've got this supplement—say, a vitamin C pill or something similar—that uses something called liposomes to deliver the nutrients into your body. If you've never heard of liposomes, no worries; most people haven't. Think of them as these tiny, bubble-like spheres made from fats, kind of like the natural stuff that makes up the walls of your body's cells. They're basically little protective packages.Here's how it works: Normally, when you swallow a regular vitamin pill, a lot of the good stuff gets destroyed by your stomach acid or doesn't get absorbed well, so your body only uses a small part of it. But with liposomes, the nutrient—like the vitamin—is tucked safely inside that fatty bubble. This bubble shields it from all the harsh digestive juices as it travels through your gut.Then, when it reaches your intestines or bloodstream, the liposome acts like a smart delivery system. It can either merge right into your cell walls (since it's made of similar fats) or get pulled inside the cells through a natural process. Boom—the nutrient gets released directly where your body needs it, without much waste. That means you absorb way more of it, sometimes several times better than a standard pill, so you feel the benefits faster and stronger.It's like wrapping a fragile gift in bubble wrap to make sure it arrives in one piece. Gentle on your tummy too, and great for things like boosting your immune system or energy. Pretty cool, right? If you're trying a product like this for the first time, start with the recommended dose and see how it works for you!

Below is a curated list of 20 scientific articles focused on the advantages of using liposomes as a delivery mechanism for Whole food Fulvic Acid, Probiotics, Vitamin C, Vitamin B, Curcumin, and Nitric Oxide from Beetroot. Note that research on liposomal delivery is abundant for some (e.g., Vitamin C, Curcumin, Probiotics), but limited for others (e.g., Whole food Fulvic Acid and Beetroot-derived Nitric Oxide, where studies often focus on general nitric oxide delivery or related nitrates).

We have prioritized peer-reviewed articles from sources like PubMed/PMC, emphasizing advantages such as improved bioavailability, stability, targeted release, and enhanced therapeutic efficacy. Each example includes the title, a brief description of the key advantages discussed, and the link.

1. **Liposome-mediated encapsulation of probiotics: current status and future prospects**

Highlights how liposomes improve probiotic viability during gastrointestinal transit, enhance bioavailability, and enable targeted intestinal delivery for better gut health outcomes.

- https://pubmed.ncbi.nlm.nih.gov/40176707/

2. **pH-Responsive Probiotic-Liposome Hybrid System Synergistically Inhibits Intestinal Inflammation**

Describes liposomes' pH-sensitive release mechanism that protects probiotics from gastric acid, boosting their anti-inflammatory effects in the intestines.

- https://pubmed.ncbi.nlm.nih.gov/40474448/

3. **Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds to the Gut Microbiota**

Reviews liposomal encapsulation's role in shielding probiotics from harsh gut conditions, improving colonization and therapeutic modulation of microbiota.

- https://pubmed.ncbi.nlm.nih.gov/36986462/

4. **Co-encapsulation systems for delivery of bioactive ingredients: Formulation, application and challenges**

Discusses co-encapsulation in liposomes to enhance probiotic stability, mask off-flavors, and increase bioavailability for synergistic health benefits.

- https://pubmed.ncbi.nlm.nih.gov/35400451/

5. **Liposomal delivery enhances absorption of vitamin C into plasma and leukocytes in healthy adults**

Demonstrates liposomes increase vitamin C bioavailability by up to 1.77 times compared to non-liposomal forms, improving plasma and cellular uptake.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC11519160/

6. **Evaluation and clinical comparison studies on liposomal and non-liposomal vitamin C formulations**

Shows liposomal vitamin C offers superior oral bioavailability and reduced gastrointestinal side effects, enabling higher effective dosing.

- https://pubmed.ncbi.nlm.nih.gov/32901526/

7. **New oral liposomal vitamin C formulation: properties and bioavailability**

Examines how liposomes protect vitamin C from degradation, enhancing absorption and therapeutic potential for immune and antioxidant support.

- https://pubmed.ncbi.nlm.nih.gov/31264495/

8. **Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect Against Ischemia–Reperfusion Injury**

Illustrates liposomes' advantages in accelerating intestinal absorption and stabilizing vitamin C for better protection against oxidative stress.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC4915787/

9. **Pharmacokinetic Analyses of Liposomal and Non-Liposomal Multivitamin/Mineral Formulations**

Finds liposomal delivery of vitamin B complex improves overall bioavailability and nutrient retention compared to traditional forms.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC10347199/

10. **Current Applications of Liposomes for the Delivery of Vitamins**

Details liposomes' biocompatibility and ability to enhance vitamin B solubility and absorption, particularly for water-soluble B vitamins.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC10180326/

11. **Evaluation of liposomal B12 supplementation in a case series study**

Reports liposomal vitamin B12 increases absorption and bioavailability, beneficial for correcting deficiencies with fewer doses.

- https://www.oatext.com/evaluation-of-liposomal-b12-supplementation-in-a-case-series-study.php

12. **Liposomal Mineral Absorption: A Randomized Crossover Trial**

While focused on minerals, it extends to vitamin B co-delivery, showing liposomes boost cellular uptake and reduce degradation.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC9414097/

13. **The Effect of Liposomal Curcumin as an Anti-Inflammatory Strategy in the Treatment of Inflammatory Bowel Diseases**

Explains liposomes overcome curcumin's poor solubility, improving bioavailability and targeted anti-inflammatory effects in the gut.

- https://pubmed.ncbi.nlm.nih.gov/34299157/

14. **Functional liposome loaded curcumin for the treatment of experimental periodontitis**

Highlights liposomes' high loading efficiency and sustained release of curcumin, enhancing anti-inflammatory and antimicrobial benefits.

- https://pubmed.ncbi.nlm.nih.gov/37007057/

15. **Liposomes augment biological benefits of curcumin for multitargeted treatment of chronic wounds and burns**

Demonstrates liposomal curcumin provides controlled release, better penetration, and synergistic anti-inflammatory/antibacterial actions.

https://www.sciencedirect.com/science/article/pii/S0939641119308392

16. **Nitric Oxide Loaded Echogenic Liposomes for Nitric Oxide Delivery and Enhancement of Sonodynamic Therapy**

Shows liposomal encapsulation protects nitric oxide, enabling targeted delivery for vasodilation and improved therapeutic efficacy.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC3108325/

17. **Liposome-Encapsulated ISMN: A Novel Nitric Oxide-Based Therapeutic Approach against Staphylococcus aureus Biofilms**

Illustrates liposomes' stability for nitric oxide delivery, disrupting biofilms more effectively than free forms.

- https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092117

18. **Recent advances in diverse nanosystems for nitric oxide delivery in cancer therapy**

Reviews liposomal nitric oxide systems' advantages in reprogramming tumor environments and overcoming resistance via precise delivery.

- https://www.sciencedirect.com/science/article/pii/S2211383522004828

19. **The impact of humic and fulvic acids on the dynamic properties of liposome membranes: The ESR method**

Explores how fulvic acid interacts with liposomes to enhance membrane stability, suggesting potential for improved delivery of fulvic acid itself.

- https://pubmed.ncbi.nlm.nih.gov/24830871/

20. **Characterization of Fulvic Acid Beverages by Mineral Profile and Antioxidant Capacity**

While not exclusively liposomal, it discusses fulvic acid's compatibility with delivery systems like liposomes for enhanced mineral bioavailability and antioxidant effects.

- https://pmc.ncbi.nlm.nih.gov/articles/PMC6963745/

21 Liposome: classification, preparation, and applications

**Notes**:

- All articles are from reputable scientific sources and emphasize liposomal benefits like increased bioavailability, protection from degradation, and targeted action.

- Links verified as of September 18, 2025.

FulviSomes combines Fulvic Acid with liposomal technology, ensuring nutrients reach the cellular level for maximum health benefits.

It's a natural compound from humification, rich in nutrients, enhancing cellular health, soil fertility, and overall organism vitality.

Liposomes act as carriers, delivering nutrients directly through cell membranes, enhancing bioavailability and overcoming resistance to synthetic compounds.

Yes, from digestive health to skin care and respiratory support, FulviSomes offers versatile wellness solutions.

While generally beneficial, always consult with a healthcare provider, especially if you have specific health conditions or are pregnant or breastfeeding.

Follow the specific product's dosage recommendations and application methods for optimal benefits.

You can buy our products online through our flagship store or check with local health stores like Wellvita, Faithful to Nature, or The Good Stuff. For exact locations or specific local issues, please provide more details about your area.

FulviSomes are derived from natural substances and generally well-tolerated. However, individual responses can vary; consult a professional if unsure.

Yes, but for best results and to avoid potential interactions, consult with a healthcare professional.

Yes, use code FULVIVITALITY for a 20% discount on your first purchase, valid until midnight on February 10, 2025.

Cellular capability makes Fulvisomes great!

Combining the benefits of Fulvic Acid with stable liposomes, in the nano-particle size range, we offer a range of products that work at a cellular level in all living organisms. The significance of this is that we are able to transport the benefits of Fulvic Acid, and other bio-active compounds, right to where it matters. We are able to achieve this through the digestive system, the skin and nasal applications.

What is Fulvic Acid?

When organic material breaks down due to humification (e.g. composting) it forms compounds that are collectively called Humic Substances or Humates. There are thousands of molecular structures that qualify as Humic Substances. They can be classified into two main categories i.e. High molecular weight, which means Humic Acid is only soluble in water at high pH, and Fulvic Acid which are low molecular Humic Substances soluble in water at all pH values.

Because modern farming methods have disturbed the natural ecological cycle, soil has become sterile and depleted of nutrients. Artificial fertilizers are used to attempt to replenish the soil. Initially crop yields improve, but over time soil are stripped of essential trace elements that are not available in fertilisers.

Extraction process is unique

Because trace elements are essential in all metabolic processes, when Humic Acid and Fulvic Acid and/ or their salts are reintroduced to modern farming methods, the results are spectacular. Bioteq extracts Humic Substances (Humic Acid, Fulvic Acid and their salts) from fossilised plant material that is millions of years old. We are the only company in the world that manipulates the extraction process to suit the application.

Fulvic Acid then goes on to improve performance on a cellular level ensuring the health of all living organisms.

The Liposome difference

The word Liposome is derived from Lipo, which mean fat or oil, and – somes, which refers to a spherical vessel. A liposome is a Phospholipid (fatty) bilayer in water. It means that a Phosphate (water soluble) entity is attached to a fatty acid molecule (water insoluble). The size of the Liposomal sphere is the important factor. It needs to be in nano size range to enable it to penetrate through cell membranes. Once it is of the correct size, it is the most effective delivery system for anything that needs to be delivered at a point in the living organism where it is most needed.

Since all living organisms build up a resistance against synthetically produced chemicals and pharmaceuticals, it is important to overcome this resistance. The “Trojan Horse” characteristic of Liposomes achieves just that. The stability of Liposomes is important in order for this technology to be applied successfully.

This provides unlimited wellness application opportunities!